Many pathogens exist for a certain period of time or for propagation within host cells. However, they have to leave the host cell to continue their life cycle. Therefore, the exit from the host cell is closely linked to microbial pathogenesis and is crucial for the spread of the disease. The aim of the research in the Priority Programme is to investigate the exit strategies of pathogens, including infectious agents of diseases such as malaria, tuberculosis and typhoid fever. Therefore, the spectrum of pathogen exit pathways will be characterized, the molecular mechanisms mediating the exit from the host cell will be identified, and the relationship between exit strategy and disease progression will be uncovered.
more...zu: DFG Priority Programme: "Exit Strategies of Intracellular Pathogens"