Originalarbeiten
Sassmannshausen, J., Bennink, S., Distler, U., Küchenhoff, J., Minns, A.M., Lindner, S.E., Burda, P.-C., Tenzer, S., Tim W. Gilberger, T.W., Pradel, G. (2023). Comparative proteomics of vesicles essential for the egress of Plasmodium falciparum gametocytes from red blood cells. Mol Microbiol, in press.
Ernest M., Rosa, T.F.A., Rajeshkumar Pala Z., Kudyba, H.M., Sweeney, B., Reiss, T., Pradel, G., Vega-Rodríguez, J. (2023). Plasmodium falciparum Gametes and Sporozoites Hijack Plasmin and Factor H To Evade Host Complement Killing. Microbiol Spectr 11:e0449322. doi: 10.1128/spectrum.04493-22.
Saini, M., Ngwa, C.J., Marothia, M., Verma, P., Ahmad, S., Kumari, J., Anand, S., Vandana, V., Goyal, B., Chakraborti, S., Pandey, K.C., Garg, S., Pati, S., Ranganathan, A., Pradel, G., Singh, S. (2023). Characterization of Plasmodium falciparum prohibitins as novel targets to block infection in humans by impairing the growth and transmission of the parasite. Biochem Pharmacol 212:115567. doi: 10.1016/j.bcp.2023.115567.
Ngwa, C.J., Stratmann, R., Musabyimana, J.P., Pannen, K., Schöbel, J.-H.; Frings, M., Schiffers, I., Quaranta, C., Koschmieder, S., Chatain, N., Pradel, G., Bolm, C. (2022). Evaluation of Chiral Organosulfur Compounds on Their Activity against the Malaria Parasite Plasmodium falciparum. Trop Med Infect Dis 7:416.
Elmaidomy, A.H., Maher Zahran, E., Soltane, R., Alasiri, A., Saber, H., Ngwa, C.J., Pradel, G., Alsenani, F., Sayed, A.M., Abdelmohsen, U.R. (2022). New halogenated compounds from Halimeda macroloba Sea-weed with potential inhibitory activity against Malaria. Molecules 27:5617
Musabyimana, J.P., Distler, U., Sassmannshausen, J., Berks, C., Manti, J., Bennink, S., Blaschke, L., Burda, P.C., Flammersfeld, A., Tenzer, S., Ngwa, C.J., Pradel, G. (2022). Plasmodium falciparum S-Adenosylmethionine synthetase is essential for parasite survival through a complex interaction network with cytoplasmic and nuclear proteins. Microorganisms 10:1419.
Roling, L., Flammersfeld, A., Pradel, G., Bennink, S. (2022). The WD40-protein PfWLP1 ensures stability of the PfCCp-based adhesion protein complex in Plasmodium falciparum gametocytes. Front Cell Infect Microbiol 12:942364.
Hanhsen, B., Farrukh, A., Pradel, G., Ngwa, C.J. (2022). The Plasmodium falciparum CCCH Zinc Finger Protein ZNF4 Plays an Important Role in Gametocyte Exflagellation through the Regulation of Male Enriched Transcripts. Cells 11:1666.
Cytotoxic potential of Nephthea sp.-derived actinomycetes supported by metabolomics analysis. Nat Prod Res 17:1-6
Thissera, B., Hallyburton, I., Ngwa, C.J., Cherif-Silini, H., Hassane, A.S.I., Anderson, M., Campbell, L.A., Mutter, N., Eshelli, M., Abdelmohsen, U.R., Yaseen, M., Pradel, G., Belbahri, L., Elgendy, B., Hegazy, L., Rateb, M.E. (2021). Potent antiplasmodial alkaloids from the rhizobacterium Pantoea agglomerans as hemozoin modulators. Bioorg Chem 115:105215.
Alhadrami, H.A., Thissera, B., Hassan, M.H.A., Behery, F.A., Ngwa J.C., Hossam M. Hassan, H.M., Pradel, G., Abdelmohsen, U.R., and Rateb, M.E. (2021). Bio-Guided Isolation of Antimalarial Metabolites from the Coculture of Two Red Sea Sponge-Derived Actinokineospora and Rhodococcus spp. Mar Drugs 19:109.
Ngwa, C.J., Gross, M.R., Musabyimana, J.P., Pradel, G., Deitsch, K.W. (2021). The Role of the histone methyltransferase PfSET10 in antigenic variation by malaria parasites: a cutionary tale. mSphere 6:e01217-20.
Alhadrami, H.A., Sayed, A.M., El-Gendy, A.O., Shamikh, Y.I., Gaber, Y., Bakeer, W., Sheirf, N.H., Attia, E.Z., Shaban, G.M., Khalifa, B.A., Ngwa, C.J., Pradel, G., Rateb, M.E., Hassan, H.M., Alkhalifah, D.H.M., Abdelmohsen, U.R., Hozzein, W.N. (2021). A metabolomic approach to target antimalarial metabolites in the Artemisia annua fungal endophytes. Sci Rep 11:2770.
Reiss T., Theis H.I., Gonzalez-Delgado A., Vega-Rodriguez J., Zipfel P.F., Skerka C., Pradel G. (2021). Acquisition of human plasminogen facilitates complement evasion by the malaria parasite Plasmodium falciparum. Eur J Immunol 51:490-493.
Njila Tchoufack E.J., Hahnfeld L., Pitschelatow G., Bennink S., Pradel G. (2020). The endoplasmic reticulum-resident serpentine receptor SR10 has important functions for asexual and sexual blood stage development of Plasmodium falciparum. Mol Biochem Parasitol 239:111315.
Basova S., Wilke N., Koch J.C., Prokop A., Berkessel A., Pradel G., Ngwa C.J. (2020). Organoarsenic Compounds with In Vitro Activity against the Malaria Parasite Plasmodium falciparum. Biomedicines 8(8):E260.
Flammersfeld, A., Panyot, A., Yamaryo-Botté, Y., Aurass, P., Przyborski, J.M., Flieger, A., Botté, C., Pradel, G. (2020). A patatin-like phospholipase functions during gametocyte induction in the malaria parasite Plasmodium falciparum. Cell Microbiol e13146.
Ngwa, C.J., Kiesow, M.J., Orchard, L.M., Farrukh, A., Llinás, M., Pradel, G. (2019). The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during Plasmodium falciparum Gametocyte Development and Transmission. Int J Mol Sci 20:pii:E5087.
Singheiser, M., Scheeder, A., Brecht, J., Tchoufack, E.J.N., Pradel, G., Ngwa, C.J. (2019). Essential oil-wax formulations as an easy to use clothing impregnating agent to prevent mosquito bites from the malaria vector Anopheles. AASCIT J Biosci 5:1-10.
Reiss, T., Rosa, T.F.A., Blaesius, K., Bobbert, R.P., Zipfel, P.F., Skerka, C., Pradel, G. (2018). Cutting Edge: FHR-1 binding impairs factor H-mediated complement evasion by the malaria parasite Plasmodium falciparum. J Immunol 201:3497-3502.
Bennink, S., von Bohl, A., Ngwa, C.J., Henschel, L., Kuehn, A., Pilch, N., Weißbach, T., Rosinski, A.N., Scheuermayer, M., Repnik, U., Przyborski, J.M., Minns, A.M., Orchard, L.M., Griffiths, G., Lindner, S.E., Llinás, M., Pradel, G. (2018). A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum. PLoS Pathog 14:e1007249.
Wezena, C.A., Alisch, R., Golzmann, A., Liedgens, L., Staudacher, V., Pradel, G., Deponte, M. (2017). The cytosolic glyoxalases of Plasmodium falciparum are dispensable during asexual blood-stage development. Microb Cell 5:32-41
Ngwa, C.J., Kiesow, M.J., Pabst, O., Orchard, L.M., Filarsky, M., Rosinski, A.N., Voss, T.S., Llinás, M., Pradel, G. (2017). Transcriptional profiling defines Histone acetylation as a regulator of gene expression during human-to-mosquito transmission of the malaria parasite Plasmodium falciparum. Front Cell Infect Microbiol 7:320
Weißbach, T., Golzmann, A., Bennink, S., Pradel, G., Ngwa, C.J. (2017). Transcript and protein expression analysis of proteases in the blood stages of Plasmodium falciparum. Exp Parasitol pii: S0014-4894(17)30170-4.
Philbert, A., Lyantagaye, S.L., Pradel, G., Ngwa, C.J., Nkwengulila, G. (2017). Pyrethroids and DDT tolerance of Anopheles gambiae s.l. from Sengerema District, an area of intensive pesticide usage in north-western Tanzania. Trop Med Int Health 22:388-398.
Jadhav, K.B., Stein, C., Makarewicz, O., Pradel, G., Lichtenecker, R.J., Sack, H., Heinemann, S.H., Arndt, H.D. (2017). Bioactivity of topologically confined gramicidin A dimers. Bioorg Med Chem 25:261-268.
Bargieri, D.Y., Thiberge, S., Tay, C.L., Carey, A.F., Rantz, A., Hischen, F., Lorthiois, A., Straschil, U., Singh, P., Singh, S., Triglia, T., Tsuboi, T., Cowman, A., Chitnis, C., Alano, P., Baum, J., Pradel, G., Lavazec, C., Ménard, R. (2016). Plasmodium merozoite TRAP family protein is essential for vacuole membrane disruption and gamete egress from erythrocytes. Cell Host Microbe 20:618-630
Schmidt, I., Pradel, G., Sologub, L., Golzmann, A., Ngwa, C.J., Kucharski, A., Schirmeister, T., Holzgrabe. U. (2016). Bistacrine derivates as new potent antimalarials. Bioorg Med Chem 24:3636-43.
von Bohl, A., Kuehn, A., Simon, N. Ngongang, V.N., Spehr, M., Baumeister, S. Przyborski, J.M., Fischer, R., Pradel, G. (2015). A WD-40-repeat protein unique to malaria parasites associates with adhesion protein complexes and is crucial for blood stage progeny. Malar J 14: 435
Rosa, T.F., Flammersfeld, A., Ngwa, C.J., Kiesow, M., Fischer, R., Skerka, C., Pradel, G. (2015). The Plasmodium falciparum blood stages acquire factor H familiy proteins to evade destruction by human complement. Cell Microbiol 18:573-590.
Simon, N., Kuehn, A., Williamson, K.C., Pradel, G. (2015). Adhesion protein complexes of malaria gametocytes assemble following parasite transmission to the mosquito. Parasitol Int 65:27-30.
Lenta, B.N., Ateba, J.T., Chouna, J.R., Aminake, M.N., Nardella, F., Pradel, G., Neumann, B., Stammler, H.G., Vonthron-Sénécheau, C., Ngouelac, S., Sewald, N. (2015) Two 2,6-Dioxabicyclo[ 3.3.1]nonan-3-ones from Phragmanthera capitate (Spreng.) Balle (Loranthaceae). Helvetica Chimica Acta 98:945-952.
Wirth, C.C., Bennink, S., Scheuermayer, M., Fischer, R., Pradel, G. (2015) Perforin-like protein PPLP4 is crucial for mosquito midgut infection by Plasmodium falciparum. Mol Biochem Parasitol 201:90-99.
Boes, A., Spiegel, H., Voepel, N., Edgue, G., Beiss, V., Kapelski, S., Fendel, R., Scheuermayer, M., Pradel, G., Bolscher, J.M., Behet, M.C., Dechering, K.J., Hermsen, C.C., Sauerwein, R.W., Schillberg, S., Reimann, A., Fischer, R. (2015). Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate-Tackling the Cocktail Challenge. PLoS One 10:e0131456.
Spiegel, H., Boes, A., Kastilan, R., Kapelski, S., Edgue, G., Beiss, V., Chubodova, I., Scheuermayer, M., Pradel, G., Schillberg, S., Reimann, A., Fischer, R. (2015). The stage-specific in vitro efficacy of a malaria antigen cocktail provides valuable insights into the development of effective multi-stage vaccines. Biotechnol J 10:1651-1659.
Onambele, L.A., Riepl, H., Fischer, R., Pradel, G., Prokop, A. Aminake, N.A. (2015). Synthesis and evaluation of antiplasmodial activity of tryptanthrin derivatives. Int J Parasitol Drug Drug Res 5:48-57.
Beiss, V., Spiegel, H., Boes, A., Kapelski, S., Scheuermayer, M., Edgue, G., Sack, M., Fendel, R., Reimann, A., Schillberg, S., Pradel, G., Fischer, R. (2015). Heat-precipitation allows the efficient purification of a functional plant-derived malaria transmission-blocking vaccine candidate fusion protein. Biotechnol Bioeng 112:1297-1305.
Boes, A., Spiegel, H., Edgue, G., Kapelski, S., Scheuermayer, M., Fendel, R., Remarque, E., Altmann, F., Maresch, D., Reimann, A., Pradel, G., Schillberg, S., Fischer R. (2014). Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits. Plant Biotechnol J 13:222-234.
Kern, S., Agarwal, S., Huber, K., Gehring, A.P., Strödke, B., Wirth, C.C., Brügl, T., Abodo, L.O., Dandekar, T., Doerig, C., Fischer, R., Tobin, A.B., Alam, M.M., Bracher, F., Pradel, G. (2014). Inhibition of the SR protein-phosphorylating CLK kinases of Plasmodium falciparum impairs blood stage replication and malaria transmission. PLoS One 9:e105732.
Ettari, R., Pinto, A., Tamborini, L., Angelo, I.C., Grasso, S., Zappalà, M., Capodicasa, N., Yzeiraj, L., Gruber, E., Aminake, M.N., Pradel, G., Schirmeister, T., De Micheli, C., Conti, P. (2014). Synthesis and biological evaluation of papain-family cathepsin L-like cysteine protease inhibitors containing a 1,4-benzodiazepine scaffold as antiprotozoal agents. ChemMedChem 9:1817-1825.
Voepel, N., Boes, A., Edgue, G., Beiss, V., Kapelski, S., Reimann, A., Schillberg, S., Pradel, G., Fendel, R., Scheuermayer, M., Spiegel, H., Fischer, R. (2014). Malaria vaccine candidate antigen targeting the pre erythrocytic stage of Plasmodium falciparum produced at high-level in plants. Biotechnol J 9:1435-1445.
Trenholme, K., Marek, L., Duffy, S., Pradel, G., Fisher, G., Hansen, F.K., Skinner-Adams, T.S., Butterworth, A., Ngwa, C.J., Moecking, J., Goodman, C.D., McFadden, G.I., Sumanadasa, S.D., Fairlie, D.P., Avery, V.M., Kurz, T., Andrews, K.T. (2014). Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules. Antimicrob Agents Chemother 58:3666-3678.
Wirth CC, Glushakova S, Scheuermayer M, Repnik U, Garg S, Schaack D, Kachman MM, Weißbach T, Zimmerberg J, Dandekar T, Griffiths G, Chitnis CE, Singh S, Fischer R, Pradel G (2014). Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of Plasmodium falciparum gametocytes. Cell Microbiol 16:709-733.
Feller T, Thom P, Koch N, Spiegel H, Addai-Mensah O, Fischer R, Reimann A, Pradel G, Fendel R, Schillberg S, Scheuermayer M, Schinkel H (2013). Plant-based production of recombinant Plasmodium surface protein pf38 and evaluation of its potential as a vaccine candidate. PLoS One 8:e79920.
Lödige M, Lewis MD, Paulsen ES, Esch HL, Pradel G, Lehmann L, Brun R, Bringmann G, Mueller AK (2013). A primaquine-chloroquine hybrid with dual activity against Plasmodium liver and blood stages. Int J Med Microbiol 303:539-547.
Tschan S, Brouwer AJ, Werkhoven PR, Jonker AM, Wagner L, Knittel S, Aminake MN, Pradel G, Joanny F, Liskamp RM, Mordmüller B (2013). Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors. Antimicrob Agents Chemother 57:3576-3584.
Ngwa CJ, Scheuermayer M, Mair GR, Kern S, Brügl T, Wirth CC, Aminake MN, Wiesner J, Fischer R, Vilcinskas A, Pradel G (2013). Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito. BMC Genomics 14:256.
Ngwa CJ, Glöckner V, Abdelmohsen UR, Scheuermayer M, Fischer R, Hentschel U, Pradel G (2013) . 16S rRNA gene-based identification of Elizabethkingia meningoseptica (Flavobacteriales: Flavobacteriaceae) as a dominant midgut bacterium of the Asian malaria vector Anopheles stephensi (Dipteria: Culicidae) with antimicrobial activities. J Med Entomol 50:404-414.
Deligianni E, Morgan RN, Bertuccini L, Wirth CC, Silmon de Monerri NC, Spanos L, Blackman MJ, Louis C, Pradel G, Siden-Kiamos I (2013). A perforin-like protein mediates disruption of the erythrocyte membrane during egress of Plasmodium berghei male gametocytes. Cell Microbiol 15:1438-1455.
Simon N, Lasonder E, Scheuermayer M, Kuehn A, Tews S, Fischer R, Zipfel PF, Skerka C, Pradel G (2013). Malaria parasites co-opt human factor H to prevent complement-mediated lysis in the mosquito midgut. Cell Host Microbe 13(1):29-41.
Aminake MN, Mahajan A, Kumar V, Hans R, Wiesner L, Taylor D, de Kock C, Grobler A, Smith PJ, Kirschner M, Rethwilm A, Pradel G, Chibale K (2012). Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy. Bioorg Med Chem 20:5277-5289.
Röhrich CR, Ngwa CJ, Wiesner J, Schmidtberg H, Degenkolb T, Kollewe C, Fischer R, Pradel G, Vilcinskas A (2012). Harmonine, a defence compound from the harlequin ladybird, inhibits mycobacterial growth and demonstrates multi-stage antimalarial activity. Biol Lett 8:308-311.
Solyakov L, Halbert J, Alam MM, Semblat JP, Dorin-Semblat D, Reininger L, Bottrill AR, Mistry S, Abdi A, Fennell C, Holland Z, Demarta C, Bouza Y, Sicard A, Nivez MP, Eschenlauer S, Lama T, Thomas DC, Sharma P, Agarwal S, Kern S, Pradel G, Graciotti M, Tobin AB, Doerig C (2011). Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum. Nat Commun 2:565.
Humeida H, Pradel G, Stich A, Krawinkel MB (2011). The effect of glucose and insulin on in vitro proliferation of Plasmodium falciparum. J. Diabetol 3:6.
Sologub L, Kuehn A, Kern S, Przyborski J, Schillig R, Pradel G (2011). Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito. Cell Microbiol 13:897-912.
Agarwal S, Kern S, Halbert J, Przyborski JM, Baumeister S, Dandekar T, Doerig C, Pradel G (2011). Two nucleus-localized CDK-like kinases with crucial roles for malaria parasite erythrocytic replication are involved in phosphorylation of splicing factor. J Cell Biochem 112:1295-1310.
Coppi A, Natarajan R, Pradel G, Bennett BL, James ER, Roggero MA, Corradin G, Persson C, Tewari R, Sinnis P (2011). The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host. J Exp Med 208:341-356.
Aminake MN, Schoof S, Sologub L, Leubner M, Kirschner M, Arndt HD, Pradel G (2011). Thiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast. Antimicrob Agents Chemother 55:1338-1348.
Rupp I, Sologub L, Williamson KC, Scheuermayer M, Reininger L, Doerig C, Eksi S, Kombila DU, Frank M, Pradel G (2011). Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut. Cell Res 21:683-696.
Tischer M, Sologub L, Pradel G, Holzgrabe U (2010). The bisnaphthalimides as new active lead compounds against Plasmodium falciparum. Bioorg Med Chem 18(9):2998-3003.
Schoof S, Pradel G, Aminake MN, Ellinger B, Baumann S, Potowski M, Najajreh Y, Kirschner M, Arndt HD (2011). Antiplasmodial thiostrepton derivatives: proteasome inhibitors with a dual mode of action. Angew Chem Int Ed Engl 49(19):3317-3321.
Purcell LA, Leitao R, Ono T, Yanow SK, Pradel G, Spithill TW, Rodriguez A (2010). A putative kinase-related protein (PKRP) from Plasmodium berghei mediates infection in the midgut and salivary glands of the mosquito. Int J Parasitol 40(8):979-988.
Mitra BN, Pradel G, Frevert U, Eichinger D (2010). Compounds of the upper gastrointestinal tract induce rapid and efficient excystation of Entamoeba invadens. Int J Parasitol 40(6):751-760.
Nowotny B, Schneider T, Pradel G, Schirmeister T, Rethwilm A, Kirschner M (2010). Inducible APOBEC3G-Vif double stable cell line as a high-throughput screening platform to identify antiviral compounds. Antimicrob Agents Chemother 54:78-87.
Doerig C, Baker D, Billker O, Blackman MJ, Chitnis C, Dhar Kumar S, Heussler V, Holder AA, Kocken C, Krishna S, Langsley G, Lasonder E, Menard R, Meissner M, Pradel G, Ranford-Cartwright L, Sharma A, Sharma P, Tardieux T, Tatu U, Alano P (2009). Signalling in malaria parasites. The MALSIG consortium. Parasite 16:169-182.
Simon N, Scholz SM, Moreira CK, Templeton TJ, Kuehn A, Dude MA, Pradel G (2009). Sexual stage adhesion proteins form multi-protein complexes in the malaria parasite Plasmodium falciparum. J Biol Chem 284:14537-14546.
Dude MA, Kaeppler U, Herb M, Schiller M, Schulz F, Vedder B, Heppner S, Pradel G, Gut J, Rosenthal PJ, Schirmeister T, Leippe M, Gelhaus C (2008). Synthesis and evaluation of non-peptidic cysteine protease inhibitors of P. falciparum derived from etacrynic acid. Molecules 14:19-35.
Yanow SK, Purcell LA, Pradel G, Sato A, Rodriguez A, Lee M, Spithill TW (2008). Potent antimalarial and transmission-blocking activities of centanamycin, a novel DNA-binding agent. J Infect Dis 197:527-534.
Rupp I, Bosse R, Schirmeister T, Pradel G (2008). Effect of protease inhibitors on exflagellation in Plasmodium falciparum. Mol Biochem Parasitol 158:208-212.
Ettari R, Nizi E, Di Francesco ME, Dude MA, Pradel G, Vicík R, Schirmeister T, Micale N, Grasso S, Zappalà M (2008). Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors. J Med Chem 51:988-996.
Barthel D, Schlitzer M, Pradel G (2008). Telithromycin and quinupristin-dalfopristin induce delayed death in Plasmodium falciparum. Antimicrob Agents Chemother 52:774-777.
Scholz SM, Simon N, Lavazec C, Dude MA, Templeton TJ, Pradel G (2008). PfCCp proteins of Plasmodium falciparum: gametocyte-specific expression and role in complement-mediated inhibition of exflagellation. Int J Parasitol 38:327-340.
Pradel G, Wagner C, Mejia C, Templeton TJ (2006). Plasmodium falciparum: Co-dependent expression and co-localization of the PfCCp multi-adhesion domain proteins. Exp Parasitol 112:263-268.
Korochkina S, Barreau C, Pradel G, Jeffery E, Li J, Natarajan R, Shabanowitz J, Hunt D, Frevert U, Vernick KD (2006). A mosquito-specific protein family includes candidate receptors for malaria sporozoite invasion of salivary glands. Cell Microbiol 8:163-175.
Pradel G, Hayton K, Aravind L, Iyer LM, Abrahamsen MS, Bonawitz A, Mejia C, Templeton TJ (2004). A multidomain adhesion protein family expressed in Plasmodium falciparum is essential for transmission to the mosquito. J Exp Med 199:1533-1544.
Pradel G, Garapaty S, Frevert U (2004). Kupffer and stellate cell proteoglycans mediate malaria sporozoite targeting to the liver. Comp Hepatol 3:S47.
Pradel G, Garapaty S, Frevert U (2002). Proteoglycans mediate malaria sporozoite targeting to the liver. Mol Microbiol 45:637-651.
Pradel G, Frevert U (2001). Malaria sporozoites actively enter and pass through rat Kupffer cells prior to hepatocyte invasion. Hepatology 33:1154-1165.
Mota MM, Pradel G, Vanderberg JP, Hafalla JC, Frevert U, Nussenzweig RS, Nussenzweig V, Rodríguez A (2001). Migration of Plasmodium sporozoites through cells before infection. Science 291:141-144.
Pradel G, Schmidt R, Schachner M (2000). Involvement of L1.1 in memory consolidation after active avoidance conditioning in zebrafish. J Neurobiol 43:389-403.
Pradel G, Schachner M, Schmidt R (1999). Inhibition of memory consolidation by antibodies against cell adhesion molecules after active avoidance conditioning in zebrafish. J Neurobiol 39:197-206.
Hügel FU, Pradel G, Frevert U (1996). Release of malaria circumsporozoite protein into the host cell cytoplasm and interaction with ribosomes. Mol Biochem Parasitol 81:151-170.
Robson KJ, Frevert U, Reckmann I, Cowan G, Beier J, Scragg IG, Takehara K, Bishop DH, Pradel G, Sinden R, et al (1995). Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepatocytes. EMBO J 14:3883-38894.