Statusworkshop Eukaryontische Krankheitserreger 2016



Thursday, January 28, 2016:

12:00               Arrival & Registration – Lunch

13:50               Opening

14:00               Session I – Immunology & Vaccine Development

            Chair: Christine Skerka

14:00               Bismarck Dinko (UHAS University of Ho, Ghana)

                        Antibody responses to gametocytes in infected Ghanaian school children

14:15               Rolf Fendel (Fraunhofer IME Aachen):

Generation of fully human antibodies against the human parasite Plasmodium falciparum

14:30              Alexander Boes (Fraunhofer IME Aachen):

           The generation of a multi-stage malaria vaccine in tobacco

14:45              Emilia Gomez (University of Göttingen):

                       Cell surface structures as serologic markers for fungal infections

15:00              Luke Donald Halder (HKI Jena):

                       The early immune response by human monocytes to Candida albicans

15:15              Maria Johanna Niemiec (HKI Jena):

                       Zinc dynamics during antifungal immunity

15:30              Coffee Break

16:00              Session II –Cell Biology & Virulence Factors

           Chair: Carsten Lüder

16:00              Mario Kaoitan (HKI Jena): 

                       Promoter activity in Candida albicans: click beetle luciferase as dual reporters

16:15              Sele Mogavero (HKI Jena): 


16:30              Philipp Krämer (HKI Jena): 

                       Transcriptional fingerprinting of Candida blood infections

16:45              Falk Hillmann (HKI Jena):

The peroxiredoxin Asp f3 links oxidative stress tolerance to virulence in Aspergillus fumigatus

17:00              Jasmin Binder (University of Erlangen-Nürnberg):

Imparing fluoride export in the human-pathogenic fungus Aspergillus fumigatus mitigates voriconazole resistance

17:15              Toni Förster (HKI Jena):

                       The effect of Candidalysin on probiotic bacteria

17:30              Keynote Lecture 1

Chair: Gabriele Pradel

Marcel Deponte (University of Heidelberg):

Mitochondrial protein import - from yeast to parasitic protists

18:15              General assembly of the DGHM section members

20:00              Dinner at the restaurant “Zum goldenen Einhorn”

                       Markt 33, 52062 Aachen


Friday, January 29, 2016

9:00                Keynote Lecture 2

                       Chair: Gabriele Pradel

Gerald Spaeth (Institute Pasteur Paris):

Exploiting pathways of host/pathogen interaction for anti-leishmanial drug discovery

9:45                Session III – Complement evasion by pathogens

                       Chair: Sven Krappmann

9:45                Prasad Dasari (HKI Jena):

CRASP1 from Aspergillus fumigatus recruits factor H, FHL-1 and C4BP and inhibits C3b deposition on the fungal surface

10:00             Samyr Kenno (Innsbruck Medical University):

The Candida albicans factor H-binding molecule Hgt1p: in vitro and in vivo evidence that it functions as virulence factor

10:15              Thiago Rosa (RWTH Aachen University): 

Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement

10:30               Prasad Dasari (HKI Jena):

Pra1, the secreted Candida immune evasion protein, proteolytically cleaves complement C3 and blocks the effector function of C3a and C3b

10:45               Coffee Break

11:15               Session IV – Host-Parasite Interactions

            Chair: Joachim Morschhäuser

11:15               Nicole Engert (HKI Jena): 

Influence of hypoxia on the interaction of Candida albicans with intestinal epithelial cells

11:30               Antonia Dräger (HKI Jena):

Establishment of a commensal gut model to study interactions between C. albicans and lactobacilli

11.45               Annika Franke (HKI Jena): 

The impact of the lesion-forming toxin Ece1 on Candida albicans-macrophage interaction

12:00              Veronika Loiko (Max von Pettenkofer Institute for Hygiene and Clinical Microbiology): 

Identification of salvage mechanisms in Aspergillus fumigatus to cope with echinocandin-induced cell wall stress

12:15              Roswitha Nast (University of Göttingen):

                       Toxoplasma gondii modifies DNA-binding of STAT1

12.30              Taibur Rahman (University of Göttingen):

Intrinsic host factors trigger Toxoplasma gondii bradyzoite formation in terminally differentiated skeletal muscle cells – a study on the host cell transcriptome and metabolome

12:45              Che Julius Ngwa (RWTH Aachen University): 

Epigenetic regulations during Plasmodium falciparum gametocyte maturation and transmission

13:00               Lunch and Departure


Wir bedanken uns bei folgenden Firmen bei der Unterstützung zur Ausrichtung des Workshops:

  Sponsoren DGHM