Statusworkshop Eukaryontische Krankheitserreger 2016
Thursday, January 28, 2016:
12:00 Arrival & Registration – Lunch
13:50 Opening
14:00 Session I – Immunology & Vaccine Development
Chair: Christine Skerka
14:00 Bismarck Dinko (UHAS University of Ho, Ghana)
Antibody responses to gametocytes in infected Ghanaian school children
14:15 Rolf Fendel (Fraunhofer IME Aachen):
Generation of fully human antibodies against the human parasite Plasmodium falciparum
14:30 Alexander Boes (Fraunhofer IME Aachen):
The generation of a multi-stage malaria vaccine in tobacco
14:45 Emilia Gomez (University of Göttingen):
Cell surface structures as serologic markers for fungal infections
15:00 Luke Donald Halder (HKI Jena):
The early immune response by human monocytes to Candida albicans
15:15 Maria Johanna Niemiec (HKI Jena):
Zinc dynamics during antifungal immunity
15:30 Coffee Break
16:00 Session II –Cell Biology & Virulence Factors
Chair: Carsten Lüder
16:00 Mario Kaoitan (HKI Jena):
Promoter activity in Candida albicans: click beetle luciferase as dual reporters
16:15 Sele Mogavero (HKI Jena):
Candidalysin
16:30 Philipp Krämer (HKI Jena):
Transcriptional fingerprinting of Candida blood infections
16:45 Falk Hillmann (HKI Jena):
The peroxiredoxin Asp f3 links oxidative stress tolerance to virulence in Aspergillus fumigatus
17:00 Jasmin Binder (University of Erlangen-Nürnberg):
Imparing fluoride export in the human-pathogenic fungus Aspergillus fumigatus mitigates voriconazole resistance
17:15 Toni Förster (HKI Jena):
The effect of Candidalysin on probiotic bacteria
17:30 Keynote Lecture 1
Chair: Gabriele Pradel
Marcel Deponte (University of Heidelberg):
Mitochondrial protein import - from yeast to parasitic protists
18:15 General assembly of the DGHM section members
20:00 Dinner at the restaurant “Zum goldenen Einhorn”
Markt 33, 52062 Aachen
Friday, January 29, 2016
9:00 Keynote Lecture 2
Chair: Gabriele Pradel
Gerald Spaeth (Institute Pasteur Paris):
Exploiting pathways of host/pathogen interaction for anti-leishmanial drug discovery
9:45 Session III – Complement evasion by pathogens
Chair: Sven Krappmann
9:45 Prasad Dasari (HKI Jena):
CRASP1 from Aspergillus fumigatus recruits factor H, FHL-1 and C4BP and inhibits C3b deposition on the fungal surface
10:00 Samyr Kenno (Innsbruck Medical University):
The Candida albicans factor H-binding molecule Hgt1p: in vitro and in vivo evidence that it functions as virulence factor
10:15 Thiago Rosa (RWTH Aachen University):
Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement
10:30 Prasad Dasari (HKI Jena):
Pra1, the secreted Candida immune evasion protein, proteolytically cleaves complement C3 and blocks the effector function of C3a and C3b
10:45 Coffee Break
11:15 Session IV – Host-Parasite Interactions
Chair: Joachim Morschhäuser
11:15 Nicole Engert (HKI Jena):
Influence of hypoxia on the interaction of Candida albicans with intestinal epithelial cells
11:30 Antonia Dräger (HKI Jena):
Establishment of a commensal gut model to study interactions between C. albicans and lactobacilli
11.45 Annika Franke (HKI Jena):
The impact of the lesion-forming toxin Ece1 on Candida albicans-macrophage interaction
12:00 Veronika Loiko (Max von Pettenkofer Institute for Hygiene and Clinical Microbiology):
Identification of salvage mechanisms in Aspergillus fumigatus to cope with echinocandin-induced cell wall stress
12:15 Roswitha Nast (University of Göttingen):
Toxoplasma gondii modifies DNA-binding of STAT1
12.30 Taibur Rahman (University of Göttingen):
Intrinsic host factors trigger Toxoplasma gondii bradyzoite formation in terminally differentiated skeletal muscle cells – a study on the host cell transcriptome and metabolome
12:45 Che Julius Ngwa (RWTH Aachen University):
Epigenetic regulations during Plasmodium falciparum gametocyte maturation and transmission
13:00 Lunch and Departure
Wir bedanken uns bei folgenden Firmen bei der Unterstützung zur Ausrichtung des Workshops: