Statusworkshop Eukaryontische Krankheitserreger 2016


Thursday, January 28, 2016:

12:00 Arrival & Registration – Lunch

13:50 Opening

14:00 Session I – Immunology & Vaccine Development

Chair: Christine Skerka

14:00 Bismarck Dinko (UHAS University of Ho, Ghana)

Antibody responses to gametocytes in infected Ghanaian school children

14:15 Rolf Fendel (Fraunhofer IME Aachen):

Generation of fully human antibodies against the human parasite Plasmodium falciparum

14:30 Alexander Boes (Fraunhofer IME Aachen):

The generation of a multi-stage malaria vaccine in tobacco

14:45 Emilia Gomez (University of Göttingen):

Cell surface structures as serologic markers for fungal infections

15:00 Luke Donald Halder (HKI Jena):

The early immune response by human monocytes to Candida albicans

15:15 Maria Johanna Niemiec (HKI Jena):

Zinc dynamics during antifungal immunity

15:30 Coffee Break

16:00 Session II –Cell Biology & Virulence Factors

Chair: Carsten Lüder

16:00 Mario Kaoitan (HKI Jena):

Promoter activity in Candida albicans: click beetle luciferase as dual reporters

16:15 Sele Mogavero (HKI Jena):


16:30 Philipp Krämer (HKI Jena):

Transcriptional fingerprinting of Candida blood infections

16:45 Falk Hillmann (HKI Jena):

The peroxiredoxin Asp f3 links oxidative stress tolerance to virulence in Aspergillus fumigatus

17:00 Jasmin Binder (University of Erlangen-Nürnberg):

Imparing fluoride export in the human-pathogenic fungus Aspergillus fumigatus mitigates voriconazole resistance

17:15 Toni Förster (HKI Jena):

The effect of Candidalysin on probiotic bacteria

17:30 Keynote Lecture 1

Chair: Gabriele Pradel

Marcel Deponte (University of Heidelberg):

Mitochondrial protein import - from yeast to parasitic protists

18:15 General assembly of the DGHM section members

20:00 Dinner at the restaurant “Zum goldenen Einhorn”

Markt 33, 52062 Aachen

Friday, January 29, 2016

9:00 Keynote Lecture 2

Chair: Gabriele Pradel

Gerald Spaeth (Institute Pasteur Paris):

Exploiting pathways of host/pathogen interaction for anti-leishmanial drug discovery

9:45 Session III – Complement evasion by pathogens

Chair: Sven Krappmann

9:45 Prasad Dasari (HKI Jena):

CRASP1 from Aspergillus fumigatus recruits factor H, FHL-1 and C4BP and inhibits C3b deposition on the fungal surface

10:00 Samyr Kenno (Innsbruck Medical University):

The Candida albicans factor H-binding molecule Hgt1p: in vitro and in vivo evidence that it functions as virulence factor

10:15 Thiago Rosa (RWTH Aachen University):

Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement

10:30 Prasad Dasari (HKI Jena):

Pra1, the secreted Candida immune evasion protein, proteolytically cleaves complement C3 and blocks the effector function of C3a and C3b

10:45 Coffee Break

11:15 Session IV – Host-Parasite Interactions

Chair: Joachim Morschhäuser

11:15 Nicole Engert (HKI Jena):

Influence of hypoxia on the interaction of Candida albicans with intestinal epithelial cells

11:30 Antonia Dräger (HKI Jena):

Establishment of a commensal gut model to study interactions between C. albicans and lactobacilli

11.45 Annika Franke (HKI Jena):

The impact of the lesion-forming toxin Ece1 on Candida albicans-macrophage interaction

12:00 Veronika Loiko (Max von Pettenkofer Institute for Hygiene and Clinical Microbiology):

Identification of salvage mechanisms in Aspergillus fumigatus to cope with echinocandin-induced cell wall stress

12:15 Roswitha Nast (University of Göttingen):

Toxoplasma gondii modifies DNA-binding of STAT1

12.30 Taibur Rahman (University of Göttingen):

Intrinsic host factors trigger Toxoplasma gondii bradyzoite formation in terminally differentiated skeletal muscle cells – a study on the host cell transcriptome and metabolome

12:45 Che Julius Ngwa (RWTH Aachen University):

Epigenetic regulations during Plasmodium falciparum gametocyte maturation and transmission

13:00 Lunch and Departure

Wir bedanken uns bei folgenden Firmen bei der Unterstützung zur Ausrichtung des Workshops:

  Sponsoren DGHM